Menopause: is it appropriate to replace the hormones? All (real) risks of hormonal replacement therapy

Vampate, insomnia, extra kilos, mood changes: if menopause disorders compromise the quality of life, they intervene with the Tos , pros and cons

From a medical point of view, menopause begins when menstruation is missing for 12 months in a row. Usually, it happens between 45 and 55 years of age, after about two years of premonitory symptoms (vampires, headache, irritability, accumulation of fat around life etc.), which intensify over time but which, in the following years, attenuate … to leave room for other problems, which have an even greater impact on health.

The constellation of ailments that accompanies the end of the fertile age of women is caused by the drop in female sex hormones, which occurs when the ovaries close for “ceased activity”. In fact, there are several organs, as described in an article recently published on Nature Reviews Endocrinology edited by the doctors of the Obstetrics and Gynecology University of the University of Pisa.

Replace hormones? The adoption of a healthy lifestyle helps to contain many of the disorders related to menopause. If that’s not enough, to replace the hormones that the ovaries no longer produce doctors can prescribe hormonal replacement therapy (or TOS), based on estrogen only, or estrogen and progesterone. The question is delicate, because several studies in the past have linked it to increases in the risk of some tumors and cardiovascular diseases. “These effects depend on the doses and duration of the Tos”, explains Luca Pasina, head of the Laboratory of Clinical Pharmacology and prescriptive appropriateness of the IRCCS Mario Negri in Milan. “Currently, the relationship between the benefits and risks is considered favorable if the symptoms compromise the quality of life in an important way”.

Source : https://evidencenetwork.ca